Today at Berkeley Lab

Scientists Mining Metagenomes Find Miniature Molecular Scissors

By mining a database of microbial genomes and metagenomes managed by the Joint Genome Institute, a team of researchers has identified new CRISPR-associated enzymes in an ancient microbial lineage. Just one-third the size of the Cas9 protein — the business end of the gene-editing tool CRISPR-Cas9 — the new enzyme family, Cas14, is the smallest known functional CRISPR system. Cas14 may help improve CRISPR-based diagnostic tools. More>

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