Today at Berkeley Lab

Open and Shut: Pain Signals in Nerve Cells

Researchers collected X-ray data at the Advanced Light Source to define the structure of a closed protein gate important for neuronal signaling. This protein gate, ASIC1a, is important in sensing pain and forming memories of fear. Comparing the closed gate with previously known structures of the same gate when open, researchers now have a comprehensive picture of proton-dependent channels in neurons. More>

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