Today at Berkeley Lab

In Hopes Of Fixing Faulty Genes, One Scientist Starts With The Basics

In an interview on NPR’s Morning Edition yesterday, Jennifer Doudna, a biochemist with the Physical Biosciences Division and professor at UC Berkeley, described her research in genome editing, how it could facilitate personalized medicine, and why she decided to become a scientist. More>

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RCas9: A Programmable RNA Editing Tool

Jennifer Doudna of the Physical Biosciences Division led a study that demonstrates that the CRISPR/Cas9 protein complex, a powerful scientific tool for editing DNA instructions, can also be applied to RNA. More>

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PBD’s Susan Marqusee Named Biophysical Society Fellow

Marqusee, a faculty biologist, was named to the 2015 class of Society Fellows. Marqusee was recognized as “one of the world’s top experimentalists in the field of protein folding.” Her research to understand how a protein’s primary sequence and cellular environment effect folding and dynamics continues to have a significant impact on the field. More>

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Stimulating Insulin Production in the Fight Against Type-II Diabetes

Adult-onset diabetes affects hundreds of millions of people worldwide. New treatments have centered on targeting the human receptor protein GPR40 to enhance sugar-dependent insulin secretion. Recently, Takeda researchers published their drug’s mechanism of action using protein structures solved at the ALS’s Berkeley Center for Structural Biology. More>

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Lab Makes Three Permanent Hires Through Project SEARCH

The NERSC, Engineering, and Physical Biosciences divisions have permanently hired employees through Project SEARCH, which provides job training to individuals with developmental disabilities. Lab managers interested in participating can contact the Diversity and Inclusion Office. Entry-level positions beyond administrative roles can be explored. More>

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Startups Develop the Next Big Thing at Campus Lab

Inside Stanley Hall, which hosts UC Berkeley’s Department of Bioengineering and QB3 (which includes Berkeley Lab researchers), a number of labs are in full swing over the summer, serving research facilities for students and faculty and incubators for innovative startups that may spearhead emerging industries. More>

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Microbial-Based Antimalaria Drug Shipped to Africa

Project begun some 13 years ago by ALD for Biosciences Jay Keasling was culminated by an announcement on Tuesday that pharmaceutical company Sanofi and nonprofit health organization PATH have shipped 1.7 million treatments of semi-synthetid artemisinin. More>

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ALS Research on Ebola Featured in BBC News Story

Advanced Light Source user Erica Ollman Saphire (Scripps Institute) used the Berkeley Center for Structural Biology beamlines to study and solve structures of Ebola virus glycoprotein bound to antibodies. This work was recently featured on BBC News.

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How Sweet It is: New Tool for Sugar Transport Developed

JBEI researchers have developed a powerful new assay that enables scientists to identify and characterize the function of nucleotide sugar transporters, critical components in the biosynthesis of plant cell walls. More>

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Lab Wins Three 2014 R&D 100 Awards

Winners include a fast way to analyze the chemical composition of cells, genetic tools to improve crops, and a bioinformatics platform for screening 3-D cell culture models. The technologies could lead to advances in biofuels, food crops, drug screening, and biomaterials, and to a better understanding of microbial communities. More>

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