Today at Berkeley Lab

Screening for Disease or Toxins in a Drop of Blood

As a Lab researcher Daojing Wang and collaborators developed a multinozzle emitter array, a silicon chip that can dramatically shorten the time it takes to identify molecular components within small volumes of biological samples, such as blood or urine. Wang launched Newomics Inc. to further develop the technology and build a platform for personalized healthcare. More>

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Beyond Biofuels: ABPDU a Catalyst for Broader Bio-Based Economy

The original scope of the Advanced Biofuels Process Development Unit (ABPDU) was to tackle the barriers to biofuel commercialization. Five years in, its activities have expanded to utilize a broader range of raw materials to produce a variety of bio-based material, chemical and protein end products. To date, the ABPDU has entered into agreements with more than 30 partners. More>

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NIH Awards $6.5 Million to Enhance Structural Biology Research

The National Institutes of Health has awarded $6.5 million to the Lab to integrate existing synchrotron structural biology resources to better serve researchers. The grant will establish a center based at the Advanced Light Source called ALS-ENABLE, which will guide users through the most appropriate routes for answering their specific biological questions. More>

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Nanoscale Virus Features Reconstructed From Correlations of Scattered X-rays

As part of an international team, Lab researchers with the Center for the Advanced Mathematics for Energy Research Applications (CAMERA) contributed key algorithms which helped achieve a goal first proposed more than 40 years ago – using angular correlations of X-ray snapshots from non-crystalline molecules to determine the 3D structure of important biological objects. More>

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Maxon Named to Governor’s Advisory Committee on Precision Medicine

Biosciences ALD Mary Maxon is one of 14 people appointed by Governor Jerry Brown to serve on the Governor’s Advisory Committee on Precision Medicine. Maxon and committee members will advise on many aspects of policy issues relating to precision medicine, which aims to use advanced computing and technology to better understand, treat, and prevent disease. More>

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New Addition to Family of Light-Responsive Proteins

A study from a team of researchers led Cheryl Kerfeld (Biosciences Area) made the cover of Nature Plants. The study characterized a member of the orange carotenoid family of proteins (OCPs), which change shape in response to ambient light conditions to protect the host cyanobacteria. Understanding how OCPs work paves the way for engineering the protein. More>

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Enhancers Regulate Master Gene of Skeletal Development in Mice

Lab bioscientists collaborated on a study to better understand the elements regulating Indian hedgehog (Ihh), which encodes a protein that plays a key role in bone growth and differentiation. They showed that enhancers — snippets of DNA that increases the likelihood of a gene’s expression — work together in tissue-specific combinations to activate genes during development. More>

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Berkeley Lab Tech Brings Nobel-Winning Cryo-EM Into Sharper Focus

Berkeley Lab played a key role in the 2017 Nobel Prize in chemistry, honoring the development of cryo-EM, an imaging technique that has launched the fields of structural biology and biochemistry into an exciting new era of discovery. More>

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Agile BioFoundry Announces New Projects

The Agile BioFoundry — a consortium of nine DOE national labs, including Berkeley Lab — has received funding for seven new projects. These projects will allow industry and academic partners to utilize the Agile BioFoundry to develop novel microbial hosts and bio-products or to develop new capabilities and approaches that will advance all aspects of the bio-manufacturing cycle. More>

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Carolyn Larabell to Receive Shirley Award at ALS User Meeting

Carolyn Larabell has been selected by the Advanced Light Source Users’ Executive Committee (UEC) to receive the 2017 David A. Shirley Award for “Outstanding Scientific Achievement at the ALS” at the upcoming ALS User Meeting for establishing the National Center for X-Ray Tomography, and for her work pioneering soft X-ray tomography for imaging cells in their fully hydrated, functional state. More>.

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