Today at Berkeley Lab

Doudna Talks Gene Editing Patent With Newsweek Magazine

In this Q&A, Jennifer Doudna of the Biosciences Area discusses the recent patent ruling on the CRISPR-Cas9 technology, what work can now proceed as a result of that ruling, the kinds of developments that might be seen in the future, what her lab is working on next, and advice for other scientists navigating the patent system. More>

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Feb. 22 Biosciences Seminar on Bioethics

The Biosciences Area is hosting leading bioethics authority R. Alta Charo of the University of Wisconsin at Madison, who will discuss a survey of ethical, legal, and social issues surrounding human and nonhuman applications of genome editing and possible future directions for policy. Her talk “CRISPR Critters and Cut & Paste People” begins at 4 p.m. in the Building 50 Auditorium.

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Doudna Awarded Japan Prize for Invention of CRISPR Gene Editing

Jennifer Doudna of the Biosciences Area will share the Japan Prize with Emmanuelle Charpentier for their invention of CRISPR-Cas9, a gene-editing technology that has led to new therapies for cancer and hereditary diseases. The honors will be presented at an award ceremony on April 19 in Tokyo. More>

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CZ Biohub Awards Nearly $14.5 Million to Berkeley Researchers

Michel Maharbiz (Biosciences) is among 47 new investigators chosen by the Chan Zuckerberg Biohub to receive up to $1.5 million each to conduct cutting-edge biomedical research — with no strings attached. CZ Biohub seeks to foster unconventional scientific exploration and encourage researchers to invent new tools to accelerate the pace of discovery. More>

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LDRD ‘Beyond Petrochemicals’ Workshop on Feb. 16

The workshop takes place from 2 to 5 p.m. in the Building 50 Auditorium. Researchers are encouraged to propose projects that interface chemistry, materials, biology, and computing to develop new materials and chemicals that are environmentally friendly in production and use. The program includes short presentations, discussion, and networking. Register here. More>

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Lab Gets $4.6M in Functional Genomics Catalog Project

Berkeley Lab is set to receive $4.6 million over four years as part of an ongoing federally funded project to create a comprehensive catalog for fundamental genomics research. This latest expansion of the Encyclopedia of DNA Elements (ENCODE) project, or ENCODE 4, is funded by the National Human Genome Research Institute. More>

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Thirdhand Smoke Affects Weight, Blood Cell Development in Mice

Berkeley Lab researchers found that the sticky residue left behind by tobacco smoke led to changes in weight and blood cell count in mice. These latest findings add to a growing body of evidence that thirdhand smoke exposure may be harmful. More>

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First Visual Evidence of Physical Mechanism Controlling Gene Expression

New images are providing the first visual evidence of a long-postulated physical link by which genes can receive mechanical cues from their microenvironment. Created through the integration of a “record-breaking” six different imaging techniques, the images show thread-like cytofilaments reaching into and traversing a human breast cell’s chromatin-packed nucleus. More>

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Designed Metalloprotein Provides Stable Platform for Further Development

Bioscientists have characterized a novel self-assembling homotrimer designed by researchers at the University of Washington. The team performed X-ray crystallography of the protein at the Advanced Light Source to show that the combination of computational design and novel amino acids can be used to generate new protein function. More>

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Biosciences Area Celebrates Twitter Anniversary

The Biosciences Area launched its Twitter account @LBNLBioSci one year ago as a tool to disseminate the Area’s achievements in energy, environment and health. It has over 400 followers and is adding more each day. In celebration of the anniversary, a listicle on seven of the Area’s bacterial, fungal and microbial discoveries was created. Follow @LBNLBioSci.

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