Today at Berkeley Lab

What a Genome-Wide Screening Can Reveal about Cancer Survival

Berkeley Lab researchers have developed a 12-gene score tied to the odds of relapse-free breast cancer survival. The scoring system is based on an analysis of large genomic datasets and patient data, and it could eventually be developed for clinical use. More>

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First Visual Evidence of Physical Mechanism Controlling Gene Expression

New images are providing the first visual evidence of a long-postulated physical link by which genes can receive mechanical cues from their microenvironment. Created through the integration of a “record-breaking” six different imaging techniques, the images show thread-like cytofilaments reaching into and traversing a human breast cell’s chromatin-packed nucleus. More>

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BRAIN Neuro-Workshop Report Now Available

Participants at the June 2 multi-institutional Neuro-Workshop, hosted by the Lab’s Biological Systems & Engineering Division, discussed relevant technological capabilities for the national BRAIN Initiative and collaborative opportunities to address “grand challenges” in neuroscience in support of the Initiative. More>

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Outside In: The Secret Life of Galectin-1 and its Dual Role in the Breast

A team of researchers led by Mina Bissell in the Biological Systems and Engineering Division reported exciting data and new insights into how a lectin, Galectin-1 (Gal-1), plays a role in mammary gland branching morphogenesis and breast cancer progression. The article was featured on the August 16 cover of Proceedings of the National Academy of Science (PNAS). More>

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