Today at Berkeley Lab

New Key to Organism Complexity Identified

Eva Nogales of the Life Sciences Division, working with Michael Cianfrocco, led the discovery that TFIID transcription factor protein co-exists in two states — canonical and arranged. Furthermore, they found it is only in the arranged state that TFIID can bind to DNA and start the process by which genetic information gets copied into RNA for the production of proteins. Also working on this study were George Kassavetis, Patricia Grob, Jie Fang, Tamar Juven-Gershon and James Kadonaga. More>

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