Today at Berkeley Lab

To Revert Breast Cancer Cells, Give Them the Squeeze

UC Berkeley and Berkeley Lab researchers have put the squeeze — literally — on malignant mammary cells to guide them back into a normal growth pattern. The findings show that mechanical forces alone can revert and stop the growth of cancer cells. This change happens even though the genetic mutations responsible for malignancy remain. “We are showing that tissue organization is sensitive to mechanical inputs from the environment at the beginning stages of growth and development,” said Lab physical bioscientist Daniel Fletcher. “An early signal, in the form of compression, appears to get these malignant cells back on the right track.” More>

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